Let’s peer into to the world of our cannabis metabolism! When you eat a product containing THC, your liver goes into overdrive, converting the THC into its main active metabolite, 11-hydroxy-THC (11-OH-THC). This compound packs a punch and has a faster onset time compared to THC, making it particularly effective for those suffering from chronic pain.
While the absorption rate of 11-hydroxy-THC is relatively low, it still holds its own when it comes to inflammation. Unfortunately, this potent metabolite is not easy to keep stable outside of using solvents. But hey, that’s just the nature of the game.
Now, you might be wondering which is better for pain and stress relief, THC or 11-hydroxy THC? THC might be the more effective bet, but 11-hydroxy THC has some unique benefits. Plus, it’s not well-studied for its medicinal and therapeutic properties just yet. But let’s be real, neither is THC! So, keep an open mind, and let’s explore the fascinating world of cannabis metabolism together.
11-OH-THC: Understanding THC Edibles & Metabolites
Let’s dive into the science behind why eating a weed brownie will leave you feeling a bit more “baked” than smoking a joint. The answer lies in the amazing capabilities of our liver and 11-hydroxy-THC.
Here’s the lowdown: cannabis contains THCA, which turns into THC after being heated and aged. When THC is ingested, it’s metabolized by the liver into 11-hydroxy-THC and then 11-nor-9-carboxy-THC. This explains the key difference of 11-Hydroxy-THC vs Delta-9 THC – it lies in which part of the cannabinoid lifecycle is occurring.
But here’s where things get interesting: when you eat an edible, the THC goes through the “first-pass effect” or “first-pass metabolism” in the liver, which converts more of it into 11-hydroxy-THC. This means that ingesting THC can actually result in less THC making its way around the body, but more 11-hydroxy-THC being available in the blood.
On the other hand, when you inhale THC through smoking or vaping, it goes straight into the bloodstream, bypassing the liver’s conversion process. This means less 11-hydroxy-THC is produced and less potent effects are felt.
11-Hydroxy-THC Potency: Current Research
Studies have shown that 11-hydroxy-THC is a highly potent compound. For instance, a study published in the Journal of Clinical Investigation found that 11-OH-THC can produce a more intense psychoactive experience and faster heart rate compared to delta-9 THC. Dr. Rae, a leading researcher in the field, has noted this increased potency of 11-hydroxy-THC in creating subjective feelings of euphoria or a “high.” These findings suggest that the conversion of THC into 11-hydroxy-THC in the liver can result in a more potent and rapid onset of psychoactive effects.
In animal studies, 11-hydroxy-THC has been shown to be up to 7 times stronger than delta-9-THC. A 2020 study on rodents published in the journal Progress in Neuropsychopharmacology & Biological Psychiatry found that the potency of 11-hydroxy-THC was somewhere between 1.5 and 7 times more potent than delta-9-THC in certain animals and tests.
According to Dr. Rae, the reason behind 11-hydroxy-THC’s higher potency lies in its ability to bind more tightly to the CB1 receptor compared to delta-9. It’s like the metabolite is holding hands with the receptor and won’t let go, which means it can activate the receptor more efficiently.
11-Hydroxy-THC: When Was it Discovered?
11-hydroxy-THC might be the new cannabinoid for online brands, but researchers have known about this potent little molecule since the 1970s. In a report prepared for the United States Army’s Life Sciences Division, researchers mentioned 11-hydroxy-THC as a metabolite of THC. Cannabis scientists were already so familiar with it that it was treated as common knowledge. Since then, it has continued to be a focus of research in the pharmacology of THC for human and animal subjects. And now, with online brands starting to include it in their products, 11-hydroxy-THC is getting the attention it deserves.
Science Fact: How to Make 11-Hydroxy-THC?
In our bodies, delta 9 THC naturally breaks down into 11-hydroxy-THC, but in a laboratory, it takes a bit more work. Synthetic human digestive enzymes are used to transform delta 9 THC into 11-hydroxy-THC. While the production process is similar to what happens in our bodies, it’s important to note that contaminants can be introduced. But don’t worry, you don’t have to swear off 11-hydroxy-THC products altogether – just be sure to get it from a trusted source to ensure a pure and clean experience.
11-Hydroxy-THC: 8 Facts You Need to Know
Thinking about trying 11-OH-THC but wondering why you should choose it over Delta 9 or Delta 8 THC? Don’t worry, we’ve got you covered! While 11-OH-THC may be new to the hemp space, it’s already proving to have some unique benefits. let’s go over some key points…
#1: How Long to Feel Effects from 11-OH-THC?
Curious about how long it takes to feel the effects of 11-OH-THC? Well, it all depends on how you consume it. If you’re inhaling or vaping, you can expect to feel the effects in a matter of minutes. But if you’re indulging in some delicious 11-OH-THC edibles, be prepared to wait anywhere from 30 minutes to an hour and a half for the high to kick in. And just a heads up, the effects can be a bit unpredictable in terms of their strength. So, take it slow and steady to avoid being caught off guard.
#2: What Does 11-Hydroxy-THC Feel Like?
What are the most common 11-OH-THC effects? Well, it’s hard to say for sure since there haven’t been any definitive long-term studies, but many users report feeling a heady and intense high. The effects may include mental and physical sensations, euphoria, relaxation, and an overall intense experience.
We at Summitt Labs have our own team of brave testers who tried 11-OH-THC during our RnD stages. Here’s what we found: a heavy head high, Sativa-prominent effects, quick half-life, and intense euphoria. But keep in mind, everyone’s experience is different, and these effects are only for informational purposes.
#3: Can 11-OH-THC Show on Drug Tests?
The short answer is, yes. Just like other cannabinoids, 11-OH-THC can be detected on drug tests. Drug tests typically look for specific metabolites in the body created when a person consumes THC. 11-OH-THC is one of those metabolites that can show up on a drug test.
#4: Is 11-Hydroxy-THC Legal?
When it comes to legality, 11-hydroxy THC is just like other non-delta 9 cannabinoids found in hemp, such as delta 8 THC, THC-X, and THCV, and many others. These compounds are all federally legal under the 2018 Farm Bill, as long as they contain no more than 0.3% delta 9 THC. But wait, there’s a catch! If a state has banned delta 8 THC, it may also prohibit 11-hydroxy THC. So, before you indulge in some 11-OH-THC goodness, make sure to check the regulations in your state to ensure compliance, unless you want to end up in a legal pickle.
#5: What Makes 11-OH-THC Special?
11-Hydroxy-Δ⁹-tetrahydrocannabinol may be similar to delta 9 THC, but with a much greater kick. This cannabinoid can induce a dreamy, euphoric cerebral effect and a pronounced body high when consumed orally, making users feel like they’re floating on cloud nine. Unlike vaping or smoking cannabis, which typically have 5% 11-Hydroxy-THC levels, orally consumed cannabis products can contain much higher levels, starting from 25% THC and increasing from there. This makes for a potent experience, so newbies beware! Additionally, 11-Hydroxy-THC can more effectively cross the blood-brain barrier compared to Delta 8 or Delta 9 THC.
#6: 11-Hydroxy-THC Vape: Does it Work?
Want to experience the potent effects of 11-OH-THC without waiting for the edibles to kick in? Vaping might be the solution for you! Unlike edibles that can take some time to take effect, 11-OH-THC vape aims to deliver a quick and natural buzz. Don’t worry, 11-Hydroxy-THC won’t develop a stomach acid or anything wild. Instead, the same chemical present in THC is unlocked and made available in a convenient vape form.
#7: How to Dose 11-OH-THC?
Are you curious about how to avoid overdoing it with 11-hydroxy-THC? Don’t worry, we’ve got you covered. Many brands will offer both edibles and vapor products – it is important to know the difference.
When it comes to edibles, slow and steady wins the race. It’s best to start with a small dosage of around 2-3 mg, wait for an hour or two, and see what effect it has before consuming more. Remember, you can always take more, but you can’t take less.
Vaping 11-OH-THC is a bit different since it goes straight into your bloodstream through your lungs, rather than passing through your liver like edibles. Because of this, the effects can be unpredictable. We recommend starting with 1-2 puffs every 10 minutes or so until you reach your desired effect.
#8: Potential 11-Hydroxy-THC Side Effects
11-OH-THC, can cause some side effects. But don’t worry, most of these effects are only temporary. Here are a few common side effects you might experience:
- Anxiety: Feeling like the world is about to end? It’s possible that THC could make you feel more anxious.
- Dry mouth: Nothing a little water can’t fix. But be prepared to reach for that water bottle.
- Increased appetite and heart rate: Munchies, anyone? THC can make you feel hungry, and it can also increase your heart rate.
- Memory loss: Wait, what were we talking about again? THC can impair your short-term memory.
- Red eyes: You might look like you’ve been crying your eyes out, but don’t worry, it’s just the THC.
- Slowed reaction times: Don’t plan on driving or operating heavy machinery after consuming THC.
While cannabis overdoses have not resulted in death, it is still possible to overdo it and misuse cannabis. If you take too much, you might feel anxious, confused, or dizzy. So, take it slow and pace yourself to avoid an unpleasant experience. In rare cases, high doses of 11-Hydroxy-THC can cause hallucinations, paranoia and panic attacks, as well as nausea and vomiting. But hey, bad experiences with THC usually go away as you come down from the high. So, if you’re experiencing a bad high, try to relax and hydrate. And remember, the effects are temporary.
Buying 11-Hydroxy-THC: What to Look For?
It’s easy to fall into the trap of going for the cheapest 11-OH-THC product or settling for the first one that catches your eye. But when it comes to this powerful cannabinoid, cutting corners is a no-go. Some companies use cheap ingredients or extraction methods that can diminish the potency of the product, leaving you with a disappointing experience. Plus, there’s always the risk of fake products circulating in the market. But fear not! There are easy ways to make sure you’re getting the real deal.
Want to learn more? Check out our blog on what to look for in Delta-8 THC
Know Where You Are Sourcing From
One way to ensure you’re getting a top-notch product is by shopping with a trusted online distributor. The online hemp marketplace is incredibly competitive, so online companies have to work hard to keep up. This means higher quality standards and fresher products with more potency due to higher turnover rates.
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On the other hand, gas stations and convenience stores typically offer the cheapest delta 8 products possible, which often means a significant reduction in quality. So, don’t skimp on quality, and make sure you’re getting the real deal by shopping with a trusted online distributor.
Don’t Forget Customer Reviews
Before purchasing any 11-Hydroxy-THC products, always check out what other people are saying about the company. Customer reviews are a great way to find out about the quality of the products and the company’s overall business practices. But be sure to look beyond the reviews on the company’s website, as some of them may be fake or cherry-picked.
Fake reviews are a real bummer, but they’re not always that hard to spot. Keep an eye out for patterns like consistent tone, grammar, and punctuation across different reviews, as well as an overuse of the same words. If all the reviews are using the word “awesome” or “fantastic” repeatedly, it’s a pretty good indication that they’re fake.
Find Third-Party Lab Reports
If you’re shopping for 11-OH-THC products, there’s nothing wrong with being a little nosy. That’s why you should always look for third-party lab reports. It’s the ultimate way to know that the product you’re buying is legit.
These lab reports are like a report card for your 11-OH-THC. They show the chemical composition, impurities, and other unwanted elements that might be lurking in your product. Legitimate companies will have these reports readily available on their website. If you can’t find them, it’s time to look elsewhere because they might be hiding something.
Think of third-party lab reports as a litmus test for quality. It’s like when you’re trying to find a good dinner place, you always ask for recommendations. Well, these lab reports are your recommendations. Trust us; your body will thank you.
Read the Product Label Information
When it comes to 11-OH-THC products, don’t just focus on the cannabinoid content itself. Take a closer look at the ingredients list provided by the company, because you want to make sure that each ingredient serves a purpose and isn’t just filler material. Opt for products made with natural and safe ingredients, avoiding any chemical additives, artificial preservatives, or allergens that may cause problems.
In addition, be sure to check the milligram strength of the product, which should be clearly labeled on the package. If a product has too low a concentration of 11-OH-THC, it won’t be potent enough to give you the desired effects.
Happy Time High: The Only True 11-Hydroxy-THC for Sale
Looking for an out-of-this-world high? Look no further than Happy Time High’s mind-blowing 11-OH-THC! All their products are made with TLC and are enhanced with Live Rosin, a superior extract. Remember, it’s always happy time somewhere with Happy Time High.
Each cartridge comes packed with 3 grams of their stellar 11-hydroxy THC formula, these cartridges are free from synthetics, heavy metals, pesticides, and GMOs for a pure and clean cosmic journey. With added ceramic coils for a smooth and flavorful pull each time. Made with food-grade silicone and specialized borosilicate glass, these cartridges are luxurious and attach easily to any 510-thread device.
And if you’re on the go, their 2G disposable pen is the perfect match, doubling the blend of live rosin 11-hydroxy THC for double the flavor. With dynamic ceramic coils, an ergonomic tip, and rapid USB-C recharging, this disposable pen is easy and efficient. So why wait? Get ready for an unparalleled quality and experience that’s sure to elevate your cannabis game to new heights with Happy Time High.